Prostate Cancer Awareness
Men, your prostate is a walnut-shaped gland that is located between the bladder and penis. This gland is responsible for protecting and nourishing the sperms and contributes to the semen count. Abnormal growth in the prostate gland can either be benign (non-cancerous) or malignant (cancerous).
Among men ,prostate cancer is one of the most common cancer types. It develops when abnormal cells in the prostate gland multiply and accumulate to form a tumour.
Screening and early detection play a very crucial role in the management of prostate cancer as the disease can be managed in the early stages through minimal medical intervention. Hence, being aware of the risk factors, early warning signs, screening and treatment methodologies are crucial to manage it and reduce morbidity. Yes death .
News update Methylsulfonylmethane (Organic Sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells.
Karolina Kowalska et al. Environ Toxicol Pharmacol. 2018 Dec.
A major challenge in the management of prostate cancer (PC) is to limit tumor growth and metastases. Targeted therapies applying natural compounds might be potentially useful in PC treatment. Methylsulfonylmethane (MSM), also known as organic sulfur, is a dietary supplement used for various clinical purposes, mostly known for its anti-inflammatory properties. Therefore, we decided to evaluate the effect of MSM on PC cells LNCaP, PC3 and DU-145 which represent different in vitro models of PC. We observed that MSM decreases the viability and invasiveness of PC cells through the induction of apoptosis and cell cycle arrest in the G0/G1 cell cycle phase. Moreover, MSM in a low dose (200 mM) is able to reduce the migration and invasion of PC cells. Considering the low overall body toxicity and insignificant side effects of MSM, its apoptosis-inducing properties might be used in PC treatment in the future.
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